Based in the dusty plains of North India, Guddu Rangeela is a story about two cousins trying to make ends meet in the crime infested surroundings. Rangeela (Arshad Warsi) and Guddu (Amit Sadh) are orchestra singers by day and informants by night, acquiring measly pay offs from the information provided to local gangsters about the richest families in town, has fetched them an easy and safe way to subsist without getting their hands dirty in the bargain. Although cousins by blood, both are very much unlike each other. The love hate rapport of the two comes to be seen through the many dangerously funny circumstances that they are met with and their impromptu methods of saving their skin each time. Having suffered a tragic past at the hands of the gang lord turned politician Billu Pahalwan (Ronit Roy); the antagonist of the tale; both are discreetly entangled in a 10-year-old legal battle against him through Gupta, an honest advocate fighting on their behalf.